• Title of article

    Design and synthesis of β-carboxamido phosphonates as potent inhibitors of imidazole glycerol phosphate dehydratase

  • Author/Authors

    Barbara A. Schweitzer، نويسنده , , Paul J. Loida، نويسنده , , Rebecca L. Thompson-Mize، نويسنده , , Claire A. CaJacob، نويسنده , , Shridhar G. Hegde، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    6
  • From page
    2053
  • To page
    2058
  • Abstract
    We describe the synthesis and enzymatic activity of a library of β-carboxamido phosphonates as inhibitors of imidazole glycerol phosphate dehydratase (IGPD). Biological results suggest the presence of an enzymatic interaction site not previously observed for other inhibitors of IGPD.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1999
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790283

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=790283