Author/Authors :
Thierry Dubuffet، نويسنده , , Adrian Newman-Tancredi، نويسنده , , Didier Cussac، نويسنده , , Valérie Audinot، نويسنده , , Annie Loutz، نويسنده , , Mark J. Millan، نويسنده , , Gilbert Lavielle، نويسنده ,
Abstract :
A new series of benzopyrano[3,4-c]pyrrole derivatives were synthesized and evaluated for their interaction with dopamine D3versus D2 receptors. Amongst these compounds, 4x (S 33084) was found to be a potent and selective dopamine D3 receptor antagonist.