Author/Authors :
T. K. Vinh، نويسنده , , M. Ahmadi، نويسنده , , P. O. Lopez Delgado، نويسنده , , S. Fernandez Perez، نويسنده , , H. M. Walters، نويسنده , , H. J. Smith، نويسنده , , P. J. Nicholls، نويسنده , , C. Simons، نويسنده ,
Abstract :
The synthesis of a series of novel 1-[(benzofuran-2-yl)phenylmethyl]-triazoles and -tetrazoles is described. The compounds were tested for human placental aromatase inhibition in vitro, using [1β-3H]-androstenedione as the substrate for the aromatase enzyme, the percentage inhibition and IC50 data is included.