Title of article
1-[(Benzofuran-2-yl)phenylmethyl]-triazoles and -tetrazoles - potent competitive inhibitors of aromatase
Author/Authors
T. K. Vinh، نويسنده , , M. Ahmadi، نويسنده , , P. O. Lopez Delgado، نويسنده , , S. Fernandez Perez، نويسنده , , H. M. Walters، نويسنده , , H. J. Smith، نويسنده , , P. J. Nicholls، نويسنده , , C. Simons، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
2105
To page
2108
Abstract
The synthesis of a series of novel 1-[(benzofuran-2-yl)phenylmethyl]-triazoles and -tetrazoles is described. The compounds were tested for human placental aromatase inhibition in vitro, using [1β-3H]-androstenedione as the substrate for the aromatase enzyme, the percentage inhibition and IC50 data is included.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790293
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