Title of article
Novel conformationally restricted tetracyclic analogs of Δ8-tetrahydrocannabinol
Author/Authors
Atmaram D. Khanolkar، نويسنده , , Dai Lu، نويسنده , , Pusheng Fan، نويسنده , , Xiaoyu Tian، نويسنده , , Alexandros Makriyannis، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
2119
To page
2124
Abstract
Novel analogs of (−)-Δ8-tetrahydrocannabinol (Δ8-THC) in which the conformation of the side chain was restricted by incorporating the first one or two carbons into a six membered ring fused with the aromatic phenolic A ring were synthesized. The affinities of the novel ligands for CB1 and CB2 indicated that the “southbound” chain conformer retained the highest affinity for both receptors
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790296
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