Author/Authors :
Massmi Ishibashi، نويسنده , , Hiroko Oda، نويسنده , , Mana Mitamura، نويسنده , , Emi Okuyama، نويسنده , , Kanki Komiyama، نويسنده , , Kiichiro Kawaguchi، نويسنده , , Takashi Watanabe، نويسنده , , Sérgio de Mello Alves، نويسنده , , Toshiro Maekawa، نويسنده , , Kenzo Ohtsuki، نويسنده ,
Abstract :
Two dihydroflavonol rhamnosides (1 and 2) isolated from the bark of Hymenaea parvifolia and two pentacyclic triterpenoids (3 and 6) obtained from the leaves of Wulffia baccata have been found to exhibit inhibitory effects of casein kinase II (CK-II) dose-dependently, suggesting that at higher doses more than 10 μM, these four compounds may act as potent CK-II suppressors of the CK-II mediated activation of 60S acidic ribosomal P proteins in vitro.
