Author/Authors :
David A. Johnson، نويسنده , , C. Gregory Sowell، نويسنده , , Craig L. Johnson، نويسنده , , Mark T. Livesay، نويسنده , , David S. Keegan، نويسنده , , Michael J. Rhodes، نويسنده , , J. Terry Ulrich، نويسنده , , Jon R. Ward، نويسنده , , John L. Cantrell، نويسنده , , Valerie G. Brookshire، نويسنده ,
Abstract :
A novel series of acylated ω-aminoalkyl 2-amino-2-deoxy-4-phosphono-β-D-glucopyranosides (aminoalkyl glucosaminide 4-phosphates) was synthesized and screened for immunostimulant activity. Several of these compounds enhance the production of tetanus toxoid-specific antibodies in mice and augment vaccine-induced cytotoxic T cells against EG.7-ova target cells.
