Title of article
2,7-Diazabicyclo[3.3.0]octanes as novel h5-HT1D receptor agonists
Author/Authors
Michael G.N. Russell، نويسنده , , Margaret S. Beer، نويسنده , , Josephine A. Stanton، نويسنده , , Bindi Sohal، نويسنده , , Russell J. Mortishire-Smith، نويسنده , , José L. Castro، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
2491
To page
2496
Abstract
The conformational restriction of a (benzylamino)methyl substituted pyrrolidine to form 2,7-diazabicyclo[3.3.0]octanes has led to a series of compounds with high affinity at the h5-HT1D receptor as well as dramatically increased concentrations in the hepatic portal vein following oral administration.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790361
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