Title of article :
6-Arylamino-5,8-quinolinediones and 7-arylamino-5,8-isoquinolinediones as inhibitors of endothelium-dependent vasorelaxation
Author/Authors :
Chung-Kyu Ryu، نويسنده , , Sung-Hee Jung، نويسنده , , Joung-Ah Lee، نويسنده , , Hwa-Jung Kim، نويسنده , , Soo-Hwan Lee، نويسنده , , Jin Ho Chung، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Abstract :
6-Arylamino-5,8-quinolinediones 3 and 7-arylamino-5,8-isoquinolinediones 4 were synthesized as inhibitors of endothelium-dependent vasorelaxation. The quinones inhibited the vasorelaxation of rat aorta with the endothelium. Among them, the quinones 3a, 3b, 3f, 4b, 4d and 4g strongly inhibited the vasorelaxation.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
