Author/Authors :
Ae Nim Pae، نويسنده , , Hye Yeon Kim and Frederick T. Sheldon ، نويسنده , , Hyun Jin Joo، نويسنده , , Bo Hyung Kim، نويسنده , , Yong Seo Cho، نويسنده , , Kyung Il Choi، نويسنده , , Jung Hoon Choi، نويسنده , , Hun Yeong Koh، نويسنده ,
Abstract :
Two series of oxazolidinone derivatives having substituted isoxazoles were synthesized and tested for antibacterial activities against several Gram-positive strains including the resistant strains of Staphylococcus and Enterococcus, such as MRSA, CRSA, MSSA and VRE. Some of them showed in vitro activities (MIC) comparable or superior to the reference compound vancomycin.
