Title of article
Synthesis and in vitro activity of new oxazolidinone antibacterial agents having substituted isoxazoles
Author/Authors
Ae Nim Pae، نويسنده , , Hye Yeon Kim and Frederick T. Sheldon ، نويسنده , , Hyun Jin Joo، نويسنده , , Bo Hyung Kim، نويسنده , , Yong Seo Cho، نويسنده , , Kyung Il Choi، نويسنده , , Jung Hoon Choi، نويسنده , , Hun Yeong Koh، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
2679
To page
2684
Abstract
Two series of oxazolidinone derivatives having substituted isoxazoles were synthesized and tested for antibacterial activities against several Gram-positive strains including the resistant strains of Staphylococcus and Enterococcus, such as MRSA, CRSA, MSSA and VRE. Some of them showed in vitro activities (MIC) comparable or superior to the reference compound vancomycin.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790405
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