Title of article
3D QSAR studies on new oxazolidinone antibacterial agents by comparative molecular field analysis
Author/Authors
Ae Nim Pae، نويسنده , , Su Yeon Kim ، نويسنده , , Hye Yeon Kim and Frederick T. Sheldon ، نويسنده , , Hyun Jin Joo، نويسنده , , Yong Seo Cho، نويسنده , , Kyung Il Choi، نويسنده , , Jung Hoon Choi، نويسنده , , Hun Yeong Koh، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
2685
To page
2690
Abstract
Three-dimensional QSAR studies for two series of new oxazolidinone antibacterial agents were conducted using the comparative molecular field analysis (CoMFA). In vitro activities (MICs) of the compounds against methicillin-resistant Staphylococcus aureus 88 (MRSA 88) exhibited a strong correlation with their steric, electrostatic factors and lipophilicities.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790406
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