Author/Authors :
Ae Nim Pae، نويسنده , , Su Yeon Kim ، نويسنده , , Hye Yeon Kim and Frederick T. Sheldon ، نويسنده , , Hyun Jin Joo، نويسنده , , Yong Seo Cho، نويسنده , , Kyung Il Choi، نويسنده , , Jung Hoon Choi، نويسنده , , Hun Yeong Koh، نويسنده ,
Abstract :
Three-dimensional QSAR studies for two series of new oxazolidinone antibacterial agents were conducted using the comparative molecular field analysis (CoMFA). In vitro activities (MICs) of the compounds against methicillin-resistant Staphylococcus aureus 88 (MRSA 88) exhibited a strong correlation with their steric, electrostatic factors and lipophilicities.
