Title of article
2-Naphthylcarbapenems: Broad spectrum antibiotics with enhanced potency against MRSA
Author/Authors
Mark L. Greenlee، نويسنده , , Frank DiNinno، نويسنده , , Jeffrey J. Herrmann، نويسنده , , Cynthia Jaworsky، نويسنده , , David A. Muthard، نويسنده , , Thomas N. Salzmann، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
2893
To page
2896
Abstract
A regioisomeric set of 2-naphthylcarbapenems featuring cationic substituents was synthesized. Optimal placement of the cationic group was found to markedly improve activity against methicillin-resistant staphylococci while maintaining a good spectrum of gram-negative activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790448
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