Stabilization of microtubules by combretastatin D derivatives
Author/Authors :
Elias A. Couladouros، نويسنده , , Tianhu Li، نويسنده , , Vassilios I. Moutsos، نويسنده , , Emmanuel N. Pitsinos، نويسنده , , Ioanna C. Soufli، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Pages :
2
From page :
2927
To page :
2928
Abstract :
The effect of five derivatives of Combretastatin D on tubulin polymerization was investigated. All of them were found to stabilize microtubules to various degrees. The derivatives bearing polar substituents were found to be the most active.
