Title of article
Nonpeptidic SH2 inhibitors of the tyrosine kinase ZAP-70
Author/Authors
Chi B. Vu، نويسنده , , Evelyn G. Corpuz، نويسنده , , Selvaluxmi G. Pradeepan، نويسنده , , Shelia Violette، نويسنده , , Catherine Bartlett، نويسنده , , Tomi K. Sawyer، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
3009
To page
3014
Abstract
The synthesis of a series of 1,2,4-oxadiazole analogs is discussed along with their ZAP-70 SH2 inhibitory activity. The tyrosine moiety in the original series has been replaced with nonpeptidic functional groups without a substantial loss of binding affinity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790470
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