Title of article
The oxetane conformational lock of paclitaxel: Structural analysis of D-secopaclitaxel
Author/Authors
Thomas C. Boge، نويسنده , , Michael Hepperle، نويسنده , , David G. Vander Velde، نويسنده , , Christopher W. Gunn، نويسنده , , Joanne M. Caine and Gary L. Grunewald، نويسنده , , Gunda I. Georg، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
3041
To page
3046
Abstract
Analysis of the1H NMR data of paclitaxel in comparison with its oxetane ring-opened analogue D-secopaclitaxel suggests that the oxetane moiety (D-ring) of paclitaxel serves as a conformational lock for the diterpene moiety and the C13 side chain.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790477
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