• Title of article

    4-Chlorobenzyl sulfonamide and sulfamide derivatives of histamine homologues: The design of potent histamine H3 receptor antagonists

  • Author/Authors

    Matthew J. Tozer، نويسنده , , Ildiko M. Buck، نويسنده , , Tracey Cooke، نويسنده , , S. Barret Kalindjian، نويسنده , , Iain M. McDonald، نويسنده , , Michael J. Pether، نويسنده , , Katherine I. M. Steel، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    6
  • From page
    3103
  • To page
    3108
  • Abstract
    4-Chlorophenylmethanesulfonamide and (4-chlorobenzyl)sulfamide derivatives of histamine homologues were prepared and found to be potent and selective histamine H3 receptor antagonists. High receptor affinity and low differences in the data from the bioassays were achieved with the imidazol-4-ylbutyl analogues.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1999
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790488