Author/Authors :
Sang-sup Jew، نويسنده , , Chi-hyoung Yoo، نويسنده , , Doo-yeon Lim، نويسنده , , Heeman Kim، نويسنده , , Inhee Mook-Jung، نويسنده , , Min Whan Jung، نويسنده , , Heesung Choi، نويسنده , , Young Hoon Jung، نويسنده , , Heedoo Kim، نويسنده , , Hyeung-geun Park، نويسنده ,
Abstract :
8 Semi-synthetic derivatives of asiatic acid were prepared and their protective effect against Aβ-induced neurotoxicity was evaluated. Among them, asiatic acid (Figure 1 and Scheme 1), and 4, 16 showed 97, 92 and 87% of protective effect, respectively.