• Title of article

    Bioisosteric modification of PETT-HIV-1 RT-inhibitors: synthesis and biological evaluation

  • Author/Authors

    Marita H?gberg، نويسنده , , Per Engelhardt، نويسنده , , Lotta Vrang، نويسنده , , Hong Zhang، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    265
  • To page
    268
  • Abstract
    Bioisosteric substitution of the thiourea (3, 5, 7, 9) and urea (10) moiety of PETT compounds with sulfamide (1), cyanoguanidine (2, 4) and guanidine (6, 8) functionalities, and replacement of the phenethyl group with benzoylethyl group (compounds 11–20) have been studied. Synthesis and antiviral activities are described. Scheme 3. Scheme 1. Scheme 2.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2000
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790618

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=790618