Author/Authors :
Karin M. Edvinsson، نويسنده , , Margareta Hersl?f، نويسنده , , Patrik Holm، نويسنده , , Nina Kann، نويسنده , , David J. Keeling، نويسنده , , Jan P. Mattsson، نويسنده , , Bo Nordén، نويسنده , , Vladimir Shcherbukhin، نويسنده ,
Abstract :
Unsymmetrical diamide libraries have been prepared by a general and versatile solid phase route, using diacid templates in combination with aromatic and aliphatic amines chosen with the help of statistical experimental design. The compounds were tested as potential inhibitors of osteoclast vacuolar ATPase.