Title of article
soniazid-related copper(II) and nickel(II) complexes with antimycobacterial in vitro activity. Part 9
Author/Authors
B. Bottari، نويسنده , , R. Maccari، نويسنده , , F. Monforte، نويسنده , , R. Ottanà، نويسنده , , E. Rotondo، نويسنده , , M. G. Vigorita، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
657
To page
660
Abstract
Isonicotinoylhydrazones 1, obtained by the primary antituberculous agent Isoniazid, have been used as monoanionic ligands (L) to prepare copper(II) 2 and nickel(II) 3 octahedral complexes of stoichiometry [MeL2(H2O)2]. Their antimycobacterial in vitro activity was evaluated against Mycobacterium tuberculosis H37Rv in comparison with the ligands. Complexes 2a, 2b, 2f, 3b, 3d and 3g displayed MIC values 0.2 μg/mL.
Scheme 1.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790708
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