• Title of article

    Eryloside F, a novel penasterol disaccharide possessing potent thrombin receptor antagonist activity

  • Author/Authors

    Paul Stead، نويسنده , , Steve Hiscox، نويسنده , , Phil S. Robinson، نويسنده , , Nicholas B. Pike، نويسنده , , Philip J. Sidebottom، نويسنده , , Andrew D. Roberts، نويسنده , , Nicholas L. Taylor، نويسنده , , Amy E. Wright، نويسنده , , Shirley A. Pomponi، نويسنده , , David Langley، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    661
  • To page
    664
  • Abstract
    We report the discovery of Eryloside F, a novel disaccharide of the steroidal carboxylic acid penasterol, isolated from an extract of the marine sponge Erylus formosus. The compound is a potent thrombin receptor antagonist, and furthermore inhibits human platelet aggregation in vitro.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2000
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790709