Title of article
4-Thiazolidinones: novel inhibitors of the bacterial enzyme murB
Author/Authors
Charles J. Andres، نويسنده , , Joanne J. Bronson، نويسنده , , Stanley V. DʹAndrea، نويسنده , , Milind S. Deshpande، نويسنده , , Paul J. Falk، نويسنده , , Katharine A. Grant-Young، نويسنده , , William E. Harte، نويسنده , , Hsu-Tso Ho، نويسنده , , Peter F. Misco، نويسنده , , James G. Robertson، نويسنده , , David Stock، نويسنده , , Yaxiong Sun، نويسنده , , Ann W. Walsh، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
3
From page
715
To page
717
Abstract
4-Thiazolidinones were synthesized and evaluated for their ability to inhibit the bacterial enzyme MurB. Selected 4-thiazolidinones displayed activity against the enzyme in vitro. This activity, coupled with the design principles of the thiazolidinones, supports the postulate that 4-thiazolidinones may be recognized as diphosphate mimics by a biological selector.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790722
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