Author/Authors :
Haydee Ch?vez، نويسنده , , Gladis Rodr?guez، نويسنده , , Ana Estévez-Braun، نويسنده , , Angel G. Ravelo، نويسنده , , Rafael Estévez-Reyes، نويسنده , , Antonio G. Gonzalez، نويسنده , , Jose L. Fdez-Puente، نويسنده , , Dolores Garc?a-Gr?valos، نويسنده ,
Abstract :
Macrocarpins A (1), B (2), C ( 3) and D ( 4), four new nor-triterpenes, have been isolated from the roots of Maytenus macrocarpa. The structures were established by spectroscopic examinations. Natural compounds 1, 2, 4 and the acetyl derivative 1a are cytotoxic against four tumoral cell lines with IC50 values ranging between 0.4 and 5.2 μM.
Figure 1. C–H long range correlations.
Figure 2. Selected NOEs observed.
