Title of article
Synthesis of glycosylated polyethylenimine with reduced toxicity and high transfecting efficiency
Author/Authors
Françoise Leclercq، نويسنده , , Catherine Dubertret، نويسنده , , Bruno Pitard، نويسنده , , Daniel Scherman، نويسنده , , Jean Herscovici، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
3
From page
1233
To page
1235
Abstract
A safe and efficient synthesis of glycosylated polyethylenimine using titanium (IV) isopropoxide and sodium borohydride has been carried out as a substitute for the highly toxic sodium cyanoborohydride method currently used. Polyplexes formed between DNA and the various glycosylated polyethylenimines appeared to be much less cytotoxic than polyethylenimine (PEI)/DNA polyplexes.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790840
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