Title of article
Discovery of a potent, non-triketone type inhibitor of 4-hydroxyphenylpyruvate dioxygenase
Author/Authors
Shean-woei Lin، نويسنده , , Yun-Loung Lin، نويسنده , , Tzu-Ching Lin، نويسنده , , Ding-Yah Yang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
2
From page
1297
To page
1298
Abstract
3-Cyclopropanecarbonyloxy-2-cyclohexen-1-one has been found to be a new, potent, low molecular weight non-triketone type inhibitor of 4-hydroxyphenylpyruvate dioxygenase with IC50 value of 30 nM. Preliminary studies suggest that the two carbonyl groups present in the compound are crucial for the inhibition activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790856
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