Title of article
Thiosugars. Part 5: synthesis and biological activity of 1-(4-thio- -arabinofuranosyl)-5-halopyrimidine nucleosides
Author/Authors
J?rn Wirsching، نويسنده , , Jürgen Voss، نويسنده , , Jan Balzarini، نويسنده , , Erik De Clercq، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
3
From page
1339
To page
1341
Abstract
1-O-Acetyl-2,3,5-tri-O-benzyl-4-thio- -arabinofuranoside (6) was transformed in two steps into the 1-(4-thio- -arabinofuranosyl)-5-halopyrimidine nucleosides 10, 11 and 12, obtained as anomeric mixtures which were separable in the case of 10 and 11. No in vitro antiviral activity against HIV-1 and HIV-2, TK+- and TK− VZV and CMV has been found for 10, 11 and 12.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790866
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