A new synthetic approach to 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) derivatives via a [2+2+2] cycloaddition reaction

Tetrahydroisoquinoline-3-carboxylic acid derivatives are prepared via a [2+2+2] cycloaddition reaction as a key step using Wilkinsonʹs and CpCo(CO)2 catalysts.