Title of article
Synthesis of feruloyl-myo-inositols and their inhibitory effects on superoxide generation
Author/Authors
Asao Hosoda، نويسنده , , Eisaku Nomura، نويسنده , , Akira Murakami، نويسنده , , Koichi Koshimizu، نويسنده , , Hajime Ohigashi، نويسنده , , Kazuhiko Mizuno، نويسنده , , Hisaji Taniguchi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
1439
To page
1442
Abstract
Ester compounds consisting of ferulic acid and myo-inositol, obtained from rice bran, were synthesized. The inhibitory effects of these feruloyl-myo-inositols on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced superoxide (O2−) generation were examined using differentiated HL-60 cells. Among the derivatives tested, only 3,4,5,6-tetra-O-acetyl-1,2-di-O-[3-(4′-acetoxy-3′-methoxyphenyl)-2-propenoyl]-myo-inositol (3) showed a distinct inhibitory activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790891
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