• Title of article

    Novel nikkomycin analogues: inhibitors of the fungal cell wall biosynthesis enzyme chitin synthase

  • Author/Authors

    Kikoh Obi، نويسنده , , Jun-ichiro Uda، نويسنده , , Kazuhiko Iwase، نويسنده , , Osamu Sugimoto، نويسنده , , Hiroyuki Ebisu، نويسنده , , Akira Matsuda and Fuyuhiko Inagaki، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    1451
  • To page
    1454
  • Abstract
    A series of novel nikkomycin analogue inhibitors of the chitin synthase of fungal cell wall was synthesized and evaluated for their inhibitory activities. Among them, the compound having a phenanthrene group at the terminal amino acid was found to possess strong anti-chitin synthase activity.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2000
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790894