Title of article :
Acid catalyzed michael additions to artemisitene
Author/Authors :
Jingyuan Ma، نويسنده , , Everett Weiss، نويسنده , , Dennis E. Kyle، نويسنده , , Herman Ziffer، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2000
Abstract :
A series of 14-substituted-artemisinin and 9-epiartemisinin derivatives was prepared by a titanium-tetrachloride catalyzed addition of trimethylsilyl enol ethers to artemisitene. Several compounds were four to seven times more active than artemisinin against Plasmodium falciparum.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
