Author/Authors :
Shinichi Uesato، نويسنده , , Yutaka Kitagawa، نويسنده , , Yukihiko Hara، نويسنده , , Harukuni Tokuda، نويسنده , , Masato Okuda، نويسنده , , Xiao Yang Mou، نويسنده , , Teruo Mukainaka، نويسنده , , Hoyoku Nishino، نويسنده ,
Abstract :
As an exploratory investigation of antitumor promoting compounds, 3-O-acyl-(−)-epigallocatechins possessing a straight-, branched-, phenyl-inserted- or 1,4-phenylene-inserted-acyl chain of varying length from C4 to C18 were synthesized and evaluated their inhibitory effects against the activation of the Epstein–Barr virus early antigen (EBV-EA). It was indicated that the epigallocatechin derivatives having the straight- or branched-acyl chain of C8 to C11 carbon atoms achieve marked effects.
