• Title of article

    Synthesis and evaluation of Aza HUN-7293

  • Author/Authors

    Dale L. Boger، نويسنده , , Yan Chen، نويسنده , , Carolyn A. Foster، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    1741
  • To page
    1744
  • Abstract
    The aza analogue of the cyclic heptadepsipeptide HUN-7293 (1), which is a potent naturally occurring inhibitor of inducible cell adhesion molecule expression, and its C23 (MLEU3 C2) epimer were prepared via solution-phase synthesis. Biological evaluations of these two compounds as inhibitors of cell adhesion molecules expression are detailed.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2000
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    790964