Title of article
Synthesis and monoamine transporter affinity of 2β-carbomethoxy-3β-(2″-, 3″- or 4″-substituted) biphenyltropanes
Author/Authors
Gilles Tamagnan، نويسنده , , Ronald M. Baldwin، نويسنده , , Nora S. Kula، نويسنده , , Ross J. Baldessarini، نويسنده , , Robert B. Innis، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
3
From page
1783
To page
1785
Abstract
A series of 11 novel 3β-substituted biphenyltropanes was synthesized and evaluated by selective radioligand binding assays for affinity to monoamine transporters. Both 5-HTT potency and selectivity for 5-HTT over DAT was greatest with electron withdrawing group at the 3″-position.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790975
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