Title of article :
Synthesis and HIV-1 integrase inhibitory activities of caffeoylglucosides
Author/Authors :
Sun Nam Kim، نويسنده , , Jae Yeol Lee، نويسنده , , Hyoung Ja Kim، نويسنده , , Cha-Gyun Shin، نويسنده , , Hokoon Park، نويسنده , , Yong Sup Lee، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2000
Abstract :
Caffeoylglucosides, which have a glucose ring as a central linker, were synthesized from methyl -glucosides, and their anti-HIV-1 activities were tested. Among them, four dicaffeoylglucosides (IC50=29.1–35.1 μM), 6a, 6b, 9b and 10b, showed HIV-1 integrase inhibitory activity as potent as -chicoric acid.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
