Title of article
Pyrrolo[2,3-d]pyrimidines containing an extended 5-substituent as potent and selective inhibitors of lck I
Author/Authors
Lee D. Arnold، نويسنده , , David J. Calderwood، نويسنده , , Richard W. Dixon، نويسنده , , David N. Johnston، نويسنده , , Joanne S. Kamens، نويسنده , , Rainer Munschauer، نويسنده , , Paul Rafferty، نويسنده , , Sheldon E. Ratnofsky، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
2167
To page
2170
Abstract
Pyrrolo[2,3-d]pyrimidines containing a 5-(4-phenoxyphenyl) substituent are potent and selective inhibitors of lck in vitro; some compounds are selective for lck over src. Data are shown for two compounds demonstrating that they are potent and selective inhibitors of IL2 production in cells.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791064
Link To Document