Author/Authors :
Anker Steen J?rgensen، نويسنده , , Poul Jacobsen، نويسنده , , Lise Brown Christiansen، نويسنده , , Paul S. Bury، نويسنده , , Anders Kanstrup، نويسنده , , Susan M. Thorpe، نويسنده , , Lars N?rum، نويسنده , , Karsten Wassermann، نويسنده ,
Abstract :
A series of pyrrolo[2,1,5-cd]indolizine derivatives has been synthesized and evaluated as ligands for the estrogen receptor. Properly substituted mono- and di-hydroxy derivatives showed binding in the low nanomolar range in accordance with their structural resemblance to estrogen.
