Title of article
Synthesis and estrogen receptor binding affinities of novel pyrrolo[2,1,5-cd]indolizine derivatives
Author/Authors
Anker Steen J?rgensen، نويسنده , , Poul Jacobsen، نويسنده , , Lise Brown Christiansen، نويسنده , , Paul S. Bury، نويسنده , , Anders Kanstrup، نويسنده , , Susan M. Thorpe، نويسنده , , Lars N?rum، نويسنده , , Karsten Wassermann، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
2383
To page
2386
Abstract
A series of pyrrolo[2,1,5-cd]indolizine derivatives has been synthesized and evaluated as ligands for the estrogen receptor. Properly substituted mono- and di-hydroxy derivatives showed binding in the low nanomolar range in accordance with their structural resemblance to estrogen.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791113
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