Author/Authors :
Stephen J. Shuttleworth، نويسنده , , Daniel Nasturica، نويسنده , , Christian Gervais، نويسنده , , M. Arshad Siddiqui، نويسنده , , Robert F. Rando، نويسنده , , Nola Lee، نويسنده ,
Abstract :
The synthesis of N-functionalised isatins using parallel, solution synthesis is described. Functionalised polymers were employed as stoichiometric and catalytic reagents as well as purification media in the exercise, and the derivatives were screened against a panel of serine proteases; high percentage inhibition was observed in several cases.
