Title of article
Synthesis and evaluation of 4-deacetoxyagosterol A as an MDR-modulator
Author/Authors
Nobutoshi Murakami، نويسنده , , Masanori Sugimoto، نويسنده , , Mari Morita، نويسنده , , Shin-ichi Akiyama، نويسنده , , Motomasa Kobayashi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
4
From page
2521
To page
2524
Abstract
4-Deacetoxyagosterol A was synthesized from ergosterol by utilizing reductive regioselective epoxy cleavage as a key reaction. This synthesized congener of agosterol A, a spongean MDR-modulator, showed similar MDR-modulating activity against KB CV-60 cells overexpressing MRP.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2000
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791144
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