• Title of article

    Antioxidant activity and xanthine oxidase inhibition activity of reductic acid: ascorbic acid analogue

  • Author/Authors

    Tadahiko Mashino، نويسنده , , Yasushi Takigawa، نويسنده , , Naomi Saito، نويسنده , , Liquing Q. Wong، نويسنده , , Masataka Mochizuki، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2000
  • Pages
    3
  • From page
    2783
  • To page
    2785
  • Abstract
    Reductic acid (2,3-dihydroxy-2-cyclopentenone, 1) decreased the ESR signal of 5,5-dimethyl-1-pyrroline 1-oxide (DMPO)-OH produced by hydroxyl radical and DMPO. 1 also inhibited lipid peroxidation initiated by cytochrome P450 and tert-butyl hydroperoxide. 1 inhibited xanthine oxidase activity, while ascorbic acid and 2-hydroxytetronic acid, an ascorbic acid analogue without side chain, did not.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2000
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    791204