Title of article
NO-Independent stimulators of soluble guanylate cyclase
Author/Authors
Alexander Straub، نويسنده , , Johannes-Peter Stasch، نويسنده , , Cristina Alonso-Alija، نويسنده , , Jordi Benet-Buchholz، نويسنده , , Bernhard Ducke، نويسنده , , Achim Feurer، نويسنده , , Chantal Fürstner، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
781
To page
784
Abstract
SARs around a novel type of guanylate cyclase stimulator which act by a mechanism different from classical NO-donors are described. Several pyrazolopyridinylpyrimidines are shown to relax aortic rings and revealed a long-lasting blood pressure lowering effect in rats after oral application.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791274
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