Title of article
Water-soluble propofol analogues with intravenous anaesthetic activity
Author/Authors
Andrew Cooke، نويسنده , , Alison Anderson، نويسنده , , Kirsteen Buchanan، نويسنده , , Alan Byford، نويسنده , , David Gemmell، نويسنده , , Niall Hamilton، نويسنده , , Petula McPhail، نويسنده , , Susan Miller، نويسنده , , Hardy Sundaram، نويسنده , , Peter Vijn، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
927
To page
930
Abstract
Propofol (2,6-diisopropylphenol) is a widely used intravenous anaesthetic that is formulated as an emulsion since it lacks water solubility. We report a range of water-soluble analogues of propofol, containing a para-alkylamino substituent, which retain good intravenous anaesthetic activity in rodents.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791308
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