Title of article
Synthesis and evaluation of hexahydrochrysene and tetrahydrobenzofluorene ligands for the estrogen receptor
Author/Authors
Rosanna Tedesco، نويسنده , , Michael K. Youngman، نويسنده , , Scott R. Wilson، نويسنده , , John A. Katzenellenbogen، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
1281
To page
1284
Abstract
To prepare novel estrogen receptor (ER) ligands, we have developed a facile approach to substituted hexahydrochrysene and tetrahydrobenzo[a]fluorene systems. Substituents, including basic side chains, were added to these systems, and their binding affinity to ERα and ERβ, and in some cases their transcriptional activity were evaluated.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791391
Link To Document