Synthesis and absolute configuration of Stellettadine A: A marine alkaloid that induces larval metamorphosis in Ascidians

Stellettadine A, a bisguanidinium alkaloid isolated from a marine sponge Stelletta sp. as an inducer of larval metamorphosis in ascidians, and its unnatural enantiomer were synthesized from the enantiomers of citronellal. The absolute configuration of stellettadine A was established as R.