Author/Authors :
Jeffrey M. Dener، نويسنده , , Kenneth D. Rice، نويسنده , , William S. Newcomb، نويسنده , , Vivian R. Wang، نويسنده , , Wendy B. Young، نويسنده , , Anthony R. Gangloff، نويسنده , , Elaine Y. -L. Kuo، نويسنده , , Lynne Cregar، نويسنده , , Daun Putnam، نويسنده , , Martin Wong، نويسنده ,
Abstract :
A survey of charged groups and linkers for a series of symmetrical and unsymmetrical dibasic inhibitors is described, leading to several classes of potent and selective inhibitors. In particular, the benzamidine functionality was identified as the most potent charged group investigated.
