Title of article
Novel sulfonate Derivatives: potent antimitotic agents
Author/Authors
Stephen L. Gwaltney II، نويسنده , , Hovis M. Imade، نويسنده , , Qun Li ، نويسنده , , Laura Gehrke، نويسنده , , R. Bruce Credo، نويسنده , , Robert B. Warner، نويسنده , , Jang Yun Lee، نويسنده , , Peter Kovar، نويسنده , , David Frost، نويسنده , , Shi-Chung Ng، نويسنده , , Hing L. Sham، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
3
From page
1671
To page
1673
Abstract
The synthesis and biological evaluation of novel sulfonate analogues of E-7010 are reported. Several of the compounds are potent inhibitors of cell proliferation and tubulin polymerization. Importantly, these compounds are also active against P-glycoprotein positive (+) cancer cells, which are resistant to many other antitumor agents.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791477
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