Author/Authors :
Michele A. Weidner-Wells، نويسنده , , Christine M. Boggs، نويسنده , , Barbara D. Foleno، نويسنده , , Ellyn Wira، نويسنده , , Karen Bush and Osnat Herzberg، نويسنده , , Raul M. Goldschmidt، نويسنده , , Dennis J. Hlasta، نويسنده ,
Abstract :
Oxazolidinone antibacterial agents, where the N-substituted piperazinyl group of eperezolid was replaced with a N-substituted piperidinyloxy moiety, were synthesized and shown to be active against a variety of resistant and susceptible Gram-positive organisms. The effect of ring size, positional isomerism, and fluorine substitution on antibacterial activity was examined.
