Title of article
5-HT3R Binding of lerisetron: an interdisciplinary approach to drug–Receptor interactions
Author/Authors
Harish S. Parihar، نويسنده , , Asha Suryanarayanan، نويسنده , , Chun Ma، نويسنده , , Prasad Joshi، نويسنده , , Padma Venkataraman، نويسنده , , Marvin K. Schulte، نويسنده , , Karen S. Kirschbaum، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
2133
To page
2136
Abstract
The design, synthesis, and use of lerisetron-based molecular probes to investigate the 5-HT3R binding site are described. A SAR study, which involved distance and electronic parameter modifications of lerisetronʹs N-benzyl group, resulted in the discovery of a partial agonist.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791582
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