• Title of article

    N,N-Dibenzyl-N′-benzylidenehydrazines: Potent Competitive Glucose-6-phosphatase Catalytic Enzyme Inhibitors

  • Author/Authors

    Peter Madsen، نويسنده , , Palle Jakobsen، نويسنده , , Niels Westergaard-Nielsen، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2001
  • Pages
    3
  • From page
    2165
  • To page
    2167
  • Abstract
    A novel class of N,N-dibenzyl-N′-benzylidenehydrazines as potent and competitive glucose-6-phosphatase catalytic site inhibitors are described. Optimisation of this series identified compounds with IC50 values as low as 170 nM.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2001
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    791589