Title of article :
Discovery of (R)-1-[2-Hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4-methyl-benzyl)-piperidin-4-ol: A Novel NR1/2B Subtype Selective NMDA Receptor Antagonist
Author/Authors :
Emmanuel Pinard، نويسنده , , Alexander Alanine، نويسنده , , Anne Bourson، نويسنده , , Bernd Büttelmann، نويسنده , , Ramanjit Gill، نويسنده , , Marie-Paule Heitz، نويسنده , , Georg Jaeschke، نويسنده , , Vincent Mutel، نويسنده , , Gerhard Trube، نويسنده , , René Wyler، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Pages :
4
From page :
2173
To page :
2176
Abstract :
Starting from Ro-25-6981 as a lead compound, highly potent and selective NR1/2B subtype selective NMDA receptor antagonists, with low activity at α1 adrenergic receptors were developed.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2001
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
791591
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=791591
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