Title of article
Absolute stereostructures of novel norcadinane- and trinoreudesmane-type sesquiterpenes with nitric oxide production inhibitory activity from Alpinia oxyphylla
Author/Authors
Osamu Muraoka، نويسنده , , Manabu Fujimoto، نويسنده , , Genzoh Tanabe، نويسنده , , Michinori Kubo، نويسنده , , Toshie Minematsu، نويسنده , , Hisashi Matsuda، نويسنده , , Toshio Morikawa، نويسنده , , Iwao Toguchida، نويسنده , , Masayuki Yoshikawa، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
4
From page
2217
To page
2220
Abstract
Novel 14-norcadinane-type sesquiterpenes, oxyphyllenodiols A and B, and 11,12,13-trinoreudesmane-type sesquiterpenes, oxyphyllenones A and B, were isolated from the methanolic extract of kernels of Alpinia oxyphylla. The absolute stereostructures of these norsesquiterpenes were determined on the basis of physicochemical and chemical evidence. In addition, oxyphyllenodiol A and oxyphyllenone A were found to inhibit the NO production in lipopolysaccharide-activated macrophages.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2001
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791602
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