• Title of article

    Synthesis and acetylcholinesterase inhibition of 5-desamino huperzine A derivatives

  • Author/Authors

    Klemens H?genauer، نويسنده , , Karl Baumann، نويسنده , , Albert Enz، نويسنده , , Johann Mulzer، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2001
  • Pages
    4
  • From page
    2627
  • To page
    2630
  • Abstract
    (E)- and (Z)-5-Desamino huperzine A derivatives have been synthesized using a new synthetic strategy towards the huperzine A skeleton. These derivatives showed AChE inhibition constants in the low micromolar range and thus display better activity than all previously synthesized C5 derivatives.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2001
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    791695